Courtney Elm, IT 2009
Analysis of Mechanisms for Synthesis of 1,2,4 Dithiazolidine-3,5-diones
Major
Chemical Engineering
Mentor
George Barany, Chemistry
Brief Bio
I am a 20 year old girl in IT. I enjoy riding horses, dancing with my roommate, and doing various other activities. School is ok I guess, I like to learn. I love to travel and am looking forward to seeing more of the world.
Future Plans
I intend to go to get my DMV from a Vet School after I graduate with my Chemical Engineering Degree from the U of M. I also want to start my own Vet Clinic later.
Why Research?
I got paid, and I love chemistry and thought it would be a good experience.
What Did I Get from Research?
Besides money, a lot of hands on experience with the lab and some good connections with faculty.
How Did I Start?
Many of my professors mentioned the UROP program in my freshman classes, and when I really enjoyed organic chemistry, I decided to do research with my organic professor.
My Advice for Another Student:
You get out of it what you put into it.
Research Summary
My research involves applying my skills to investigate reactions in sulfur chemistry. I examine the mechanism for synthesis of 1,2,4-dithiazolidine-3,5-diones, which are the basis of the Dts protecting group for peptide synthesis. The work involves looking for a more "green" and effective method of synthesis of the protecting group. My research on the intermediate involved in the Dts reaction will give a better understanding of the mechanism of the reaction. We will better understand how Dts is formed, and in turn how it can be formed more effectively and efficiently. This mechanism is important for Professor Barany’s peptide and DNA research, as it is a protecting group for amines. Additionally, if I am able to synthesize the derivative of Dts I am attempting, it will be a new method for the synthesis of Dts, which may be more efficient and cost-effective.